Synthesis of Polar Aromatic Substituted Terminal Alkynes from Propargyl Amine by Surya R. Banks Kyung Min Yoo & Mark E. Welker

Synthesis of Polar Aromatic Substituted Terminal Alkynes from Propargyl Amine by Surya R. Banks Kyung Min Yoo & Mark E. Welker

Author:Surya R. Banks, Kyung Min Yoo & Mark E. Welker
Format: pdf
Tags: A series of small molecules containing polar aromatic substituents and alkynes have been synthesized. One–pot preparations of polar aromatic molecules containing an alkynyl imine and alkynyl amide are reported. A one-pot preparation of a catechol containing an alkynyl amine was also attempted but in our hands it proved much better to synthesize this target molecule via a three step synthesis which we also report here., catechol; alkyne; thiol-alkyne click reaction


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